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Troponin certain to heparin brings about lower calculated troponin plasma focus when compared to serum.[seventy six] Other resources of interference which will impact the assay detection approach and lead to Bogus-unfavorable troponin values contain ascorbic acid in immunoenzymometric assays making use of alkaline phosphatase, biotin in assays utilizing a biotinylated antibody, streptokinase inside the presence of streptavidin, and significant titers of antibodies to ruthenium or streptavidin in cTnT assays.
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